Pantothenate kinase-associated neurodegeneration, PKAN (OMIM #234200), is the most common form of neurodegeneration with brain iron accumulation (NBIA), a group of rare progressive neurological disorders characterized by excess iron accumulation in the globus pallidus and, to a lesser degree, in the substantia nigra [1,2]. This evidence concerns the gene PANK1 and pantothenate kinase-associated neurodegeneration.