The translational implications of all of these studies on migration and invasion is exemplified by the ability of non-toxic AHR inhibitors to completely block metastasis of cervical (HeLa), TNBC (MDA-MB-231), and OSCC (HSC3) metastasis in a zebrafish model [107], or by AHR knockout to block melanoma metastasis to the lung [187]. The gene discussed is AHR; the disease is melanoma.