ESR1 and breast carcinoma: Kwon et al. demonstrated that ectopic CYP1B1 expression enhances Wnt/β-catenin signaling, a driver of EMT [184,185], and increased invasion in MCF10A breast epithelial cells and/or ER+ MCF7 breast cancer cells at least in part by increasing Snai1, Twist1, and Vimentin and decreasing E-cadherin expression [186].