CYP2B6 and hepatocellular carcinoma: To verify the results from the receptor activation analysis, the expression of AHR target genes, namely CYP1A1 and CYP1A2 (Figure 3B), and of the CAR target gene CYP2B6 (Figure 4B) was analyzed in the human hepatoma cell line HepaRG using quantitative real-time PCR (qRT-PCR).