SIX6 and open-angle glaucoma: In previous studies of the POAG-susceptibility loci previously associated with ED populations, several have also been associated with Asian populations including ABCA1, CAV1, CDKN2A-CDKN2B, GAS7, PMM2, TMCO1, and SIX6, while TGFβR3 has repeatedly been associated with POAG in Asian populations [43,44,50,65].