Further analysis of this duplication using real-time PCR demonstrated that the genes within the duplication (TBK1, XPOT, RASSF3 and GNS) were all expressed within the retina, suggesting a possible association with NTG and warranting further study to confirm association with either POAG or NTG specifically [64]. The gene discussed is RASSF3; the disease is open-angle glaucoma.