FNDC3B and open-angle glaucoma: A 2013 meta-analysis noted a significant association between FNDC3B and POAG (p = 5.6 × 10−4), while also noting that an allele near FNDC3B (rs4894535) associated with lower CCT actually led to a decreased POAG risk (OR 0.83, 95%CI: 0.74–0.92) [100].