They confirmed three POAG loci that were previously demonstrated in ED: CDKN2B-AS1, TMCO1, and TXNRD2. Additionally, they found an SNP (rs141186647) at a novel locus as well, EXOC4 (OR 0.48; p = 3.75 × 10−8) [53]. Here, TXNRD2 is linked to open-angle glaucoma.