Among the several therapeutic methods used to treat and control variations in blood glucose levels in humans and in experimental models with T1DM and T2DM, the most common are as follows: medication (with the use of hypoglycemic agents associated or not associated with the administration of exogenous insulin), adequate and healthy eating, regular physical activity, and/or physical exercise [12,13,14]. Here, INS is linked to type 2 diabetes mellitus.