In particular, Suriben et al. investigated the effects of an antagonistic monoclonal antibody (named 3P10), targeted to inhibit GDF-15 interaction with its receptor and coreceptor, and documented that this antibody successfully prevented GDF15-induced anorexia and, in turn, muscle loss via neuroendocrine pathways in animals [19]. Here, GDF15 is linked to Anorexia.