Consistent with previous studies (Bidault et al., 2020; Liu et al., 2019), we observed that IL6 secretion is increased in HGPS fibroblasts carrying the classical G608G LMNA mutation and also in fibroblasts from Mandibuloacral Dysplasia, another LMNA‐linked progeroid syndrome (Cenni et al., 2018; Filesi et al., 2005) (Figure 1a and Figure S1a). Here, IL6 is linked to mandibuloacral dysplasia.