FOS and atrial fibrillation: A previous study demonstrated that expression of a dominant negative form of Rho GTPase in osteoblasts blocked fluid shear stress‐induced stress fiber formation and the expression of the immediate early genes Cox2 and Fos. 57Future studies using this model system will build on the characterization of the acute effects of CTS, and specifically assess the role of Rho GTPase and the changes in cell proliferation in AF cells following chronic exposure to CTS.