The multivariate Cox regression analysis showed that age > 60 years (p < 0.001), history of hypertension (p = 0.012), history of chronic kidney disease (p < 0.001), EF (p = 0.006), TBil (p = 0.029), stent implantation (p = 0.001), Killip classification (p < 0.000), use of tirofiban during PCI (p = 0.016), coronary revascularization at admission (p = 0.003), and use of angiotensin-converting enzyme inhibitors (ACEIs) (p = 0.031) and beta-blockers (p < 0.001) remained independent risk factors associated with a high risk of mortality. The gene discussed is ACE; the disease is chronic kidney disease.