This inflammatory response includes increased levels of inflammatory markers in the blood (including C-reactive protein, ferritin, and D-dimers), increased neutrophil/lymphocyte ratio and increased serum levels of several inflammatory cytokines, for example IL-1, IL-6, and TNF-α, and chemokines, as well as extensive lymphopenia and substantial infiltration of monocytes, macrophages and neutrophils in the lungs, heart, spleen, lymph nodes, and kidney (Huang et al., 2020; Mehta et al., 2020; Merad and Martin, 2020). This evidence concerns the gene CRP and lymphopenia.