Notably, we showed CD86, IL10 of monocyte, CD163, MS4A4A, ITGAM, ITGAX of M2 Macrophage, BCL6, STAT5B, HAVCR2 of Tfh showed moderate correlate with PCOLCE expression in gastric cancer (P < 0.001; 0.40>Cor value ≥ 0.30). This evidence concerns the gene MS4A4A and gastric cancer.