CD4 and gastric cancer: Our results demonstrated that there is a moderate to strong positive relationships between PCOLCE expression level and infiltration level of CD8 + T cells (r = 0.211, P = 4.19e-05), CD4 + T cells (r = 0.227, P = 1.12e-05), neutrophils (r = 0.290, P = 1.30e-08), dendritic cell (r = 0.401, P = 9.83e-16), and macrophages (r = 0.532, P = 1.91e-28), in gastric cancer (Figure 3).