AKT1 and Sepsis: A KEGG pathway enrichment analysis with all the differentially expressed genes at a significant cut-off for adjusted P < 0.05 and q-value = 0.10, showed PI3K-Akt signaling and MAPK signaling as the top 2 pathways (i.e., highest number of genes) for the Isoflurane-Sepsis group (Supplementary Figure 2A).