NRP1 and viral infectious disease: Considering the previously described relations of exRNA to these components in provoking vascular permeability, angiogenesis, and inflammatory reactions, it is fair to propose an influence of exRNA on the VEGF-receptor-2/neuropilin-1 system in the context of virus infection, thereby enhancing the leakiness of blood vessels and promoting dissemination of virus and its penetration into tissues (Figure 5).