Dorsal root ganglion (DRG) and pancreatic cancer cell co-culture models suggested that a mutual tropism exists between the nerves/DRGs and pancreatic cancer cells through multiple molecular factors (e.g., NGF-TRKA pathway) (Ceyhan et al., 2008; Ma et al., 2008). This evidence concerns the gene NTRK1 and pancreatic neoplasm.