AKT1 and central nervous system cancer: Several previous studies have shown that miR-7-5p can inhibit the PI3K/AKT pathway in gliomas, colorectal cancer, and cardiomyocyte autophagy diseases (Kefas et al., 2008; Liu et al., 2014, 2018; Shukla et al., 2018; Cao et al., 2019).