In addition to the traditional clinicopathological risk factors, specific molecular profiles (e.g., BRAF, TERT, and RET) may be used to predict the risk of extrathyroidal extension and lymph node metastases (Xing et al., 2005; Lee et al., 2007; Kim et al., 2012). This evidence concerns the gene TERT and metastatic malignant neoplasm in the lymph nodes.