ALB and neoplasm: On the other hand, univariate analysis determined that the following factors were the important prognostic factors for RFS, including pTNM stage (II: HR = 2.19, P = 0.002; III: HR = 4.16, P = 0.008), tumor size (HR = 1.71, P= 0.005), tumor differentiation (G2: HR = 1.49, P = 0.020; G3: HR = 2.43, P = 0.003), perineural invasion (HR = 2.48, P = 0.002), vascular invasion (HR = 2.13, P = 0.001), adjuvant chemotherapy (HR = 0.79, P< 0.001), serum Alb (HR = 0.69, P< 0.001), NLR (HR = 2.33, P = 0.007), as well as LMR (HR = 1.45, 95% CI = 1.16–2.93, P = 0.003) (Table 3).