Univariate analysis indicated that the tumor size (P < 0.001), differentiation (P = 0.04), depth of invasion (P < 0.001), lymph node metastasis (P = 0.004), TNM stage (P = 0.001), postoperative recurrence (P = 0.009), and FNDC1 expression (P = 0.005) were significantly correlated with poor OS. The gene discussed is FNDC1; the disease is metastatic malignant neoplasm in the lymph nodes.