For example, adoptive transfer of 89Zr-oxine-labeled activated OT-I CD8 T cells (TCR transgenic T cells that recognize ovalbumin: OVA) shows initial rapid accumulation in the lungs, followed by gradual accumulation within antigen-expressing tumor (B16-OVA) by Day 2 (Figure 1A, right) 40. Here, CD8A is linked to neoplasm.