Patients with absolute CD4+ T-cell count of < 200 cells/μL are at an increased risk of opportunistic infections, have a higher post-transplant rejection rate and present with delayed CD4+ T-cell count recovery after the procedure.17 Although HIV infection is the primary driver of the reduced CD4+ T-cell count in PLWH, other factors may also impact the peri-transplant immune status of patients including the use of chronic haemodialysis. This evidence concerns the gene CD4 and HIV infectious disease.