confirmed the association of AGO2 with MVBs in colon cancer cells and demonstrated that the activation of KRAS‐dependent MEK‐ERK signalling was able to hamper the sorting of AGO2 and AGO2‐regulated miRNAs inside extracellular vesicles (Gibbings et al., 2009). This evidence concerns the gene AGO2 and malignant colon neoplasm.