Alterations of the quaking gene in gliomas detected during a mutational screening on primary brain tumours also exist (Li et al., 2002) high expression of QKI in tissues of breast cancer patients correlated with shorter overall survival time, proposing QKI as a prognostic marker in synergy with SLUG, a pivotal player in the EMT process (Gu et al., 2019). Here, QKI is linked to central nervous system cancer.