However, similar attempts with another such intracompartmental (intraperitoneal) delivery of 212Pb-TCMC (S-2-(4-isothiocyanatobenzyl)-1,4,7,10-tetraaza-1,4,7,10-tetra(2-carbamoylmethyl)cyclododecane)-trastuzumab in HER2 positive intraperitoneal cancers demonstrated moderate toxicity in phase 1 clinical study (NCT01384253), but no data has been published on clinical efficacy. This evidence concerns the gene ERBB2 and cancer.