Similarly, drastic tumor reductions were observed with the engagement of neutrophils with tumor cells in the presence of anti-EGFR, HER2, CD30, and Ep-CAM antibodies of IgA isotype 9, 12 possibly through the release of chemoattractant Leukotriene B4 (LTB4), which causes increased neutrophil accumulation in the tumor microenvironment 13. Here, EGFR is linked to neoplasm.