KL and neoplasm: Either NLN-KLA or NEW-KLA decreased the luminescence signals and total photon flux emitted from the whole body, as demonstrated by in vivo whole-body bioluminescence imaging (Figure 8B-C, respectively), reduced tumor volume (Figure 8D), tumor weight (Figure 8E), and number of metastatic tumor nodules (Figure 8F), while increasing percent survival (Figure 8G) and TUNEL-positive apoptotic cells (Fig. 8H), more efficiently than the combined treatment of either NLN or NEW and KLA.