For instance, miR-126-3p delivered by EC apoptosis bodies inhibits expression of regulator of G-protein signaling 16 (RGS16) to activate C-X-C motif chemokine ligand 12 (CXCL12) and its receptor, C-X-C motif chemokine receptor 4 (CXCR4), thereby reducing atherosclerosis 18. Here, RGS16 is linked to atherosclerosis.