CLU and posterior cortical atrophy: By screening lipid metabolism‐related gene sets in five independent PCa databases (TCGA Prostate, Taylor Prostate, Lapointe Prostate, Tomlins Prostate, Grasso Prostate), four genes were selected; three of these genes (ACSS3, ACSF2 and CLU) were found to be downregulated and one gene (FABP5) was found to be upregulated in PCa compared to normal prostate tissues (/FC/ > 1.5, p < 0.05) (Figure 1A).