ACSS3 and neoplasm: Our results showed that pathways related to the suppression of PCa and metastasis and pathways related to lipid metabolic processes were highly associated with high ACSS3 expression (above the 50th percentile) (Figure 2A and Figure S3A), suggesting that ACSS3, as a tumor suppressor, is involved in the regulation of tumor growth, metastasis and lipid metabolism.