CPT2 and psoriasis: Deficiencies in various circulating carnitine and acylcarnitines in psoriasis patients, as observed in the present study (Figure 4A-B), can also be explained by the increase in fatty acid oxidation in skin lesions and the increased activity of carnitine palmitoyltransferase-1 (CPT-1) 55 due to the rapidly elevated energy consumption of proliferating cells.