Moreover, cancer patients had a significant reduction in lymphocytes, including CD4+T cells (n=37 vs n=82, 370 vs 625.5 counts/μl, p<0.0001, cancer vs non-cancer) and CD8+T cells (n=43 vs n=82, 206 vs 305.0 counts/μl, p<0.0081, cancer vs non-cancer) 99. This evidence concerns the gene CD4 and cancer.