In Sardinian prostate cancers we observed an amplification in chromosome 4q13.2 which contains the UGT2 genes, UGT2B4, UGT2B7, UGT2B10, UGT2B11, UGT2A1, UGT2A2, UGT2B28, and UGT2A3 (Figure 2A&B). The gene discussed is UGT2B28; the disease is Familial prostate cancer.