DLEU2 and reading: Next, by analyzing public CRC datasets in GEPIA 34, we found that DLEU2 was significantly upregulated in colon adenocarcinoma (COAD) and rectal adenocarcinoma (READ) samples from TCGA data (p < 0.05, Fig. 2B; Supplemental Fig. 1), and that high DLEU2 expression was associated with poor RFS (p < 0.05, Fig. 2C).