To investigate the relationship between hnRNP-F and the PI3K/AKT signalling pathway in BC, no changes in the protein levels of PI3K, p-PI3K, AKT and p-AKT were observed in response to knockdown of hnRNP-F expression in the EJ and UMUC3 cell lines (P>0.05, Figure 3C). Here, AKT1 is linked to breast cancer.