Moreover, we found the LIG3 rs4796030 CC genotype carriers further increased the risk of ovarian cancer in the groups of BMI ≥ 24 (adjusted OR=2.28, 95% CI=1.14-4.58, P=0.021), clinical stages III/IV (adjusted OR=1.93, 95% CI=1.14-3.26, P=0.015) and tumor at the left (adjusted OR=2.33, 95% CI=1.34-4.06, P=0.003) when compared with the AA/AC genotype carriers. The gene discussed is LIG3; the disease is ovarian cancer.