In addition, compared with the non-AVT group, more patients in the AVT group had a family history of HCC, presence of EGV and LC, positive HBeAg, presence of MVI, and BCLC stage of 0 and A. Patients in the AVT group had a lower percentage of high HBV-DNA load (>2000 copies), high AFP level (>400 ng/mL), high AST level (>40 U/L), high ALT level (>40 U/L), presence of satellite lesions, tumor size (>5 cm), B stage of Child-Pugh score. This evidence concerns the gene AFP and hepatocellular carcinoma.