In GSE82177 dataset, the mean proportion of C06_CD4-CCR7 was 50.18% in 9 normal samples as compared to 55.51% in HCV-HCC samples (Fig. S3A), indicating an increasing proportion of C06_CD4-CCR7 in HCV-HCC than normal ones. This evidence concerns the gene CCR7 and hepatocellular carcinoma.