Further, SATB2-AS (the antisense transcript of SATB2 protein) can directly combine with WDR5 (WD repeat containing protein 5) and GADD45A (growth arrest and DNA damage protein 45A) to regulate SATB2 expression, thereby inhibiting tumor cell metastasis and regulating the tumor immune microenvironment (Xu et al., 2019). The gene discussed is WDR5; the disease is neoplasm.