Moreover, in this study, these three EGFL family members were significantly associated with immune infiltrate subtypes in the tumor microenvironment, where EGFL6 and EGFL7 were related to more aggressive subtypes of immune infiltrates, i.e., C1, C2, and C6, and were rich in IFN-r infiltration, indicating a correlation with promoting tumor progression. Here, EGFL7 is linked to neoplasm.