ST-elevation myocardial infarction (STEMI) patients with elevated inflammatory markers (e.g. hsCRP) have increased circulating IL-1β and NET-associated TF, while mouse models of thrombosis have reduced NET-associated TF and delayed thrombotic occlusion when IL-1β is blocked (193). The gene discussed is IL1B; the disease is ST Elevation Myocardial Infarction.