CFTR and cystic fibrosis: Moreover, statistical analysis revealed that CF phagosomes of neutrophils donated by PWCF receiving CFTR potentiator ivacaftor therapy illustrated phagosomal levels of hCAP-18 and MMP-9 similar to control cells, and increased compared to homozygous ΔF508 patients post 8 min phagocytosis (p = 0.01 and p = 0.04, respectively) (Figures 3C, D).