Levels of intraphagosomal MPO from primary granules was significantly increased (p = 0.03) after 8 min phagocytosis (Figures 3A, B), but in contrast, levels of hCAP-18 from secondary (p = 0.02) (Figures 3A, C) and MMP-9 from tertiary granules (p = 0.02) (Figures 3A, D) were significantly decreased in CF phagosomes compared to HC samples. Here, MPO is linked to cystic fibrosis.