Roseburia has been shown to exert beneficial effects in colitis model mice and Caco-2 cells by enhancing the anti-inflammatory response, which could reduce the DAI score by enhancing colonic Treg cell differentiation and the levels of the anti-inflammatory cytokines TSLP, IL-10, and TGF-β in the intestinal mucosa of colitis model mice (77). This evidence concerns the gene TGFB1 and colitis.