More recently, we showed that the delivery of IL‐2 and TGF-β to T cells via the use of nanoparticles (NPs) made with polymer poly(lactic‐co‐glycolic acid) (PLGA) could protect lupus mice from systemic autoimmunity by inducing Tregs - but also possibly modulating the activity of additional immune cells (10). This evidence concerns the gene IL2 and systemic lupus erythematosus.