Consistent with this previous evidence, here we found significant suppression of lung fibrosis (eg, collagen deposition area, Ashcroft and CT fibrosis score) and reduction of lung inflammation (lung cell inflammatory cells and cytokines) in TGFβ1-TG mice with pulmonary fibrosis treated with PFD (Macias-Barragan et al., 2010). This evidence concerns the gene TGFB1 and polyostotic fibrous dysplasia.