TMPRSS2 is especially an attractive target since it is not required for normal homeostasis (Ts et al., 2006); its inhibitor—camostat mesilate—is approved for human use in Japan for chronic pancreatitis, and camostat has been demonstrated to protect mice models from SARS-CoV infection (Zhou et al., 2015). Here, TMPRSS2 is linked to chronic pancreatitis.