CRP and diabetes mellitus: It is known to be influenced by several factors including age, gender, race (Greenland et al., 2018), smoking (Shaw et al., 2006), high CRP levels (defined as higher than 5 mg/L), cardiovascular disease, high blood pressure, and diabetes, although the connection between diabetes and CCS is controversial (Raggi et al., 2004; Giles et al., 2009).