It has been known that expression of hippocampal ENT-1 was elevated in patients with TLE and rat model of pilocarpine-induced epilepsy, while intrahippocampal injection of NBTI, can attenuate seizure severity and prolongs onset latency in pilocarpine-induced seizure in rats (Xu et al., 2015). Here, SLC29A1 is linked to epilepsy.