MUTYH, PTEN, RB1, TP53, and TSC1 (Table 2) genes were found to be commonly mutated in these two cell lines, supporting the proposed role of TP53, PTEN, and RB1 in the pathogenesis of human glioblastomas (Chow et al., 2011). The gene discussed is TSC1; the disease is glioblastoma.