IGF2BP1 promotes SRF expression in an m6A- and miRNA- dependent manner and subsequently promotes SRF downstream target gene including PDLIM7 and FOXK1 translation, consequently PDLIM7 and FOXK1 promote tumor cell growth and enhance cell invasion, and indicate a poor overall survival probability in liver, ovarian and lung cancer 153. This evidence concerns the gene SRF and lung cancer.