In addition, it has been reported that SNHG1 activates the Akt signaling pathway by promoting the transcription of SLC3A2 146, and then by inhibiting the function of SNHG1, it was found that consumption of SNHG1 inhibits the activation of Akt signaling pathway and enhances the association with sorafenib resistance Apoptosis and autophagy 145, so SNHG1 may become a potential target for HCC treatment. Here, AKT1 is linked to hepatocellular carcinoma.