Bioinformatics analysis showed that NEAT1 can directly target miR-335, which suppresses the proliferation, migration of cancer cell 156, and subsequent in vitro experiment showed that overexpression of NEAT1 suppress the miR-335 expression in HCC cell lines 155, indicating that miR-335 is a downstream target of NEAT1. Here, NEAT1 is linked to hepatocellular carcinoma.