Among the different subtypes of breast cancer, as described in Figure 2B, Breast Invasive Ductal Carcinoma had the highest mutation frequency of MYC, followed by Breast Invasive Mixed Mucinous Carcinoma and Breast Invasive Carcinoma (NOS), whereas Breast Invasive Lobular Carcinoma had the lowest mutation frequency of MYC. The gene discussed is MYC; the disease is breast cancer.