For example, miR-382, promotes apoptosis and autophagy in esophageal squamous cell carcinoma (ESCC) by inhibiting mTOR and 4E-BP1 50, and the overexpression of miR-382 was shown to suppress the migration, invasion and epithelial-mesenchymal transition (EMT) of ESCC cells. The gene discussed is EIF4EBP1; the disease is esophageal squamous cell carcinoma.