LINC01559 has been identified as a potential non-invasive biomarker of renal cell carcinoma and is reported to accelerate pancreatic cancer cell proliferation and invasion through enhancing YAP activity, and UNC5B-AS1 is associated with tumourigenesis and metastasis of papillary thyroid cancer 21, 23, 34. This evidence concerns the gene UNC5B and familial pancreatic carcinoma.