As shown in Figure 1, PIGR mRNA was significantly upregulated in tumor tissues compared to nontumor tissues in Guichard Liver, Guichard Liver 2 and TCGA Liver from Oncomine database (all p < 0.0001, Figure 1A), as well as in GSE55092 and GSE60502 profiles in GEO databases (both p < 0.05, Figure 1B). The gene discussed is PIGR; the disease is neoplasm.